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NME1 抗体 (Biotin)

This Biotin-conjugated 小鼠 单克隆 anti-NME1 antibody (Clone CPTC-NME1-2) specifically detects NME1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7658065
发货至: 中国
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Quick Overview for NME1 抗体 (Biotin) (ABIN7658065)

抗原

See all NME1 抗体
NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NME1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB)

克隆位点

CPTC-NME1-2
  • 原理

    NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis)(CPTC-NME1-2), Biotin conjugate

    产品特性

    The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human NME1 protein

    亚型

    IgG2a, kappa
  • 应用备注

    Western blot 0.5-1.0 μg/mL, Optimal dilution for a specific application should be determined.

    说明

    Positive Control: HepG2 and HeLa whole cell lysates, heart, brain, placenta and lung carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

    别名

    NDPK-A

    背景

    Synonyms: AWD, GAAD, Granzyme A activated DNase, Metastasis inhibition factor NM23, NB, NBS, NDP kinase A, NM23 long variant, included, NM23H1B, NME/NM23 nucleoside diphosphate kinase 1, NME1-NME2 spliced read-through transcript, included, Non-metastatic protein 23, homolog 1, Nucleoside diphosphate kinase A, Tumor metastatic process-associated protein

    Gene Symbol: NME1

    分子量

    23 kDa

    基因ID

    4830

    UniProt

    P15531

    途径

    Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
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