NME1 抗体 (CF®594)
Quick Overview for NME1 抗体 (CF®594) (ABIN7658064)
抗原
See all NME1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis)(CPTC-NME1-2), CF594 conjugate
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产品特性
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human NME1 protein
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亚型
- IgG2a, kappa
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anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 43-152) antibody
NME1 适用: 人 WB, ELISA, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 1-152) antibodyNME1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibodyNME1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibodyNME1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4B2 unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠 WB, IHC, DB 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 6-147) antibodyNME1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, 犬, 猴, Pig, Cow, 马, 兔, 小鸡, 非洲爪蟾, 斑马鱼, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (C-Term) antibodyNME1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (N-Term) antibodyNME1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 小鸡, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) (AA 137-152), (C-Term) antibodyNME1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot 0.5-1.0 μg/mL, Optimal dilution for a specific application should be determined.
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说明
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Positive Control: HepG2 and HeLa whole cell lysates, heart, brain, placenta and lung carcinoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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别名
- NDPK-A
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背景
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Synonyms: AWD, GAAD, Granzyme A activated DNase, Metastasis inhibition factor NM23, NB, NBS, NDP kinase A, NM23 long variant, included, NM23H1B, NME/NM23 nucleoside diphosphate kinase 1, NME1-NME2 spliced read-through transcript, included, Non-metastatic protein 23, homolog 1, Nucleoside diphosphate kinase A, Tumor metastatic process-associated protein
Gene Symbol: NME1
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分子量
- 23 kDa
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基因ID
- 4830
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UniProt
- P15531
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途径
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
抗原
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