NKX3-1 抗体 (AA 92-224)
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北京 101111
Quick Overview for NKX3-1 抗体 (AA 92-224) (ABIN7658043)
抗原
See all NKX3-1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 92-224
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原理
- NKX3.1 (Metastatic Prostate Adenocarcinoma Marker)(NKX3.1/2576)
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产品特性
- NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3. 1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3. 1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 92-224) of human NKX3.1 protein
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亚型
- IgG2c, kappa
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anti-NK3 Homeobox 1 (NKX3-1) (AA 100-209) antibody
NKX3-1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-NK3 Homeobox 1 (NKX3-1) antibodyNKX3-1 适用: 人 IHC, WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4H4 unconjugated
anti-NK3 Homeobox 1 (NKX3-1) (AA 92-224) antibodyNKX3-1 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal NKX3-1-2836 unconjugated
anti-NK3 Homeobox 1 (NKX3-1) (AA 92-224) antibodyNKX3-1 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal NKX3-1-2576 unconjugated
anti-NK3 Homeobox 1 (NKX3-1) (AA 92-224) antibodyNKX3-1 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal NKX3-1-3350 unconjugated
anti-NK3 Homeobox 1 (NKX3-1) (AA 118-145) antibodyNKX3-1 适用: 人 IHC, WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-NK3 Homeobox 1 (NKX3-1) antibodyNKX3-1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NK3 Homeobox 1 (NKX3-1) (N-Term) antibodyNKX3-1 适用: 人 IHC, WB, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 3-9 unconjugated
anti-NK3 Homeobox 1 (NKX3-1) (AA 118-145) antibodyNKX3-1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23610 unconjugated
anti-NK3 Homeobox 1 (NKX3-1) (Internal Region) antibodyNKX3-1 适用: 人, 小鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Highly expressed in the prostate and at a lower level in the testis.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
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别名
- NKX3.1
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背景
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Synonyms: NK3 Homeobox 1, Homeobox Protein NK-3 Homolog A, NKX3-1, NKX3A, NK3 Transcription Factor Related, Locus 1 (Drosophila), NK3 Transcription Factor Related, Locus 1, NK Homeobox (Drosophila), Family 3, A, NK3 Transcription Factor Homolog A, NK Homeobox, Family 3, A, Homeobox Protein Nkx-3.1, BAPX2, NKX3
Gene Symbol: NKX3-1
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分子量
- 35 kDa
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基因ID
- 4824
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UniProt
- Q99801
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
抗原
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