NKX2-8 抗体 (AA 10-123) (CF®568)
Quick Overview for NKX2-8 抗体 (AA 10-123) (CF®568) (ABIN7657978)
抗原
See all NKX2-8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 10-123
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原理
- NKX2.8(NKX28/2548), CF568 conjugate
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产品特性
- The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human recombinant NKX2.8 protein fragment (around aa 10-123)
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亚型
- IgG1, kappa
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应用备注
- ELISA: For coating, order antibody without BSA, Flow cytometry: 1-2 μg/million cells, Western blot 0.5-1 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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说明
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Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
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别名
- NKX2.8
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背景
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Synonyms: Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959
Gene Symbol: NKX2-8
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分子量
- 26 kDa
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基因ID
- 26257
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UniProt
- O15522
抗原
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