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NKX2-8 抗体 (AA 10-123) (CF®640R)

This anti-NKX2-8 antibody is a 小鼠 单克隆 antibody detecting NKX2-8 in WB. Suitable for 人.
产品编号 ABIN7657971
发货至: 中国

Quick Overview for NKX2-8 抗体 (AA 10-123) (CF®640R) (ABIN7657971)

抗原

See all NKX2-8 抗体
NKX2-8 (NK2 Homeobox 8 (NKX2-8))

适用

  • 65
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 40
  • 25
小鼠

克隆类型

  • 35
  • 30
单克隆

标记

  • 27
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NKX2-8 antibody is conjugated to CF®640R

应用范围

  • 52
  • 19
  • 7
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

NKX28-2547
  • 抗原表位

    • 35
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 10-123

    原理

    NKX2.8(NKX28/2547), CF640R conjugate

    产品特性

    The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human recombinant NKX2.8 protein fragment (around aa 10-123)

    亚型

    IgG1, kappa
  • 应用备注

    Western blot 0.5 μg-1 μg/mL, Optimal dilution for a specific application should be determined.

    说明

    Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    NKX2-8 (NK2 Homeobox 8 (NKX2-8))

    别名

    NKX2.8

    背景

    Synonyms: Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959

    Gene Symbol: NKX2-8

    分子量

    26 kDa

    基因ID

    26257

    UniProt

    O15522
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