Recombinant MALT1 抗体 (AA 701-808)
Quick Overview for Recombinant MALT1 抗体 (AA 701-808) (ABIN7657500)
抗原
See all MALT1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 701-808
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原理
- MALT1 (MALT-Lymphoma Marker)(rMT1/410)
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产品特性
- Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11,18)(q21,q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa701-808) of human MALT1 protein
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亚型
- IgG1, kappa
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anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 125-450) antibody
MALT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal MT1-410 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (Internal Region) antibodyMALT1 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal rMT1-410 unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 IHC (f) 宿主: 兔 Monoclonal MT1-3159R unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 685-784) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) antibodyMALT1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Jurkat, Daudi or HeLa cells. Tonsil or lymphoma.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, 0.05 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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别名
- MALT1
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背景
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Synonyms: Caspase-like protein, MALT lymphoma-associated translocation, MLT1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase
Gene Symbol: MALT1
Tissue Expression: B-cells
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分子量
- 93 kDa
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基因ID
- 10892
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UniProt
- Q9UDY8
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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