Recombinant MUC3A 抗体 (CF®740)
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北京 101111
Quick Overview for Recombinant MUC3A 抗体 (CF®740) (ABIN7657389)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MUC3 (Mucin 3)(MUC3/2992R), CF740 conjugate
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产品特性
- Recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
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亚型
- IgG
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anti-Mucin 3A, Cell Surface Associated (MUC3A) antibody
MUC3A 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal M3-1 unconjugated
anti-Mucin 3A, Cell Surface Associated (MUC3A) antibodyMUC3A 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal MUC3-1154 unconjugated
anti-Mucin 3A, Cell Surface Associated (MUC3A) (AA 1501-1600) antibodyMUC3A 适用: 人 IHC (p), IF (cc), IF (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mucin 3A, Cell Surface Associated (MUC3A) (AA 2176-2280) antibodyMUC3A 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 3A, Cell Surface Associated (MUC3A) antibodyMUC3A 适用: 人 IHC, StM 宿主: 兔 Monoclonal MUC3-2992R unconjugated Recombinant Antibody
anti-Mucin 3A, Cell Surface Associated (MUC3A) (AA 1-101) antibodyMUC3A 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 3A, Cell Surface Associated (MUC3A) (AA 2236-2356) antibodyMUC3A 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: LS174T cells. Human small intestine (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MUC3A (Mucin 3A, Cell Surface Associated (MUC3A))
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别名
- MUC3
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背景
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Synonyms: Intestinal mucin-3A, intestinal mucin-like, MUC3, MUC3A, MUC3B, mucin 3, intestinal, mucin 3A, cell surface associated, mucin 3A, intestinal, mucin 3B, cell surface associated
Gene Symbol: MUC3A
Tissue Expression: Epithelial cells|Intestine
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分子量
- 1100 kDa
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基因ID
- 4584, 57876
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UniProt
- Q02505, Q9H195
抗原
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