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Recombinant MCM7 抗体 (AA 195-319) (CF®568)

This anti-MCM7 antibody is a 小鼠 单克隆 antibody detecting MCM7 in WB, IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7657148
发货至: 中国

Quick Overview for Recombinant MCM7 抗体 (AA 195-319) (CF®568) (ABIN7657148)

抗原

See all MCM7 抗体
MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

  • 81
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单克隆

标记

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This MCM7 antibody is conjugated to CF®568

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

RMCM7-1468
  • 抗原表位

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    AA 195-319

    原理

    MCM7 (Proliferation Marker)(rMCM7/1468), CF568 conjugate

    产品特性

    The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human MCM7 protein fragment (aa195-319)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: MCF-7, HEK-293, A549, SKBr3, HeP2, Raji or Ramos cells. Tonsil (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

    别名

    MCM7

    背景

    Synonyms: CDC47, DNA replication licensing factor MCM7, MCM7 mini chromosome maintenance deficient 7, Mini chromosome Maintenance 7, Mini chromosome maintenance protein 7, P1.1-MCM3, P1CDC47, P85MCM, PNAS146

    Gene Symbol: MCM7

    分子量

    88 kDa

    基因ID

    4176

    UniProt

    P33993

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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