MCM6 抗体 (AA 228-368)
Quick Overview for MCM6 抗体 (AA 228-368) (ABIN7657135)
抗原
See all MCM6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 228-368
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原理
- MCM6 (Proliferation Marker)(MCM6/2999)
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产品特性
- The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 228-368) of human MCM6 protein
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亚型
- IgG2b, kappa
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anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibody
MCM6 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 适用: 人 WB, IF, IHC (p), PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 228-368) antibodyMCM6 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MCM6-2999 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 7D8 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 589-605), (Middle Region) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibodyMCM6 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibodyMCM6 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibodyMCM6 适用: 人, 犬, Cow, 豚鼠, 马, 兔 IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Human skin or squamous cell carcinoma (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
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别名
- MCM6
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背景
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Synonyms: DNA replication licensing factor MCM6, MCM6 minichromosome maintenance deficient 6, MIS5 homolog, p105MCM
Gene Symbol: MCM6
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分子量
- 105 kDa
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基因ID
- 4175
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UniProt
- Q14566
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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