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Recombinant TIMP2 抗体 (N-Term) (CF®568)

This anti-TIMP2 antibody is a 小鼠 单克隆 antibody detecting TIMP2 in IHC 和 IHC (fp). Suitable for 人, 大鼠, 小鼠, Cow, 兔, 斑马鱼 和 豚鼠.
产品编号 ABIN7656989
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant TIMP2 抗体 (N-Term) (CF®568) (ABIN7656989)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

抗体类型

Recombinant Antibody

适用

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人, 大鼠, 小鼠, Cow, 兔, 斑马鱼, 豚鼠

宿主

  • 146
  • 56
  • 8
  • 3
  • 1
小鼠

克隆类型

  • 128
  • 86
单克隆

标记

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This TIMP2 antibody is conjugated to CF®568

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

RTIMP2-2335
  • 抗原表位

    • 36
    • 35
    • 15
    • 15
    • 15
    • 12
    • 11
    • 7
    • 5
    • 3
    • 3
    • 3
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    • 1
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    AA 56-66, N-Term

    原理

    TIMP2 (Tissue Inhibitor of Metalloproteinase 2)(rTIMP2/2335), CF568 conjugate

    产品特性

    Recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    Synonyms: Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP2, Tissue Inhibitor of Metalloproteinase 2

    Gene Symbol: TIMP2

    分子量

    21 kDa

    基因ID

    7077

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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