MLANA 抗体 (CF®740)
Quick Overview for MLANA 抗体 (CF®740) (ABIN7656742)
抗原
See all MLANA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- MART-1 / Melan-A / MLANA (Melanoma Marker), CF740 conjugate
-
产品特性
- This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- Recombinant human full-length MLANA protein
-
亚型
- IgG, kappa
-
-
anti-Melan A (MLANA) antibody
MLANA 适用: 人, 小鼠, 大鼠 IHC, ISt, StM 宿主: 兔 Monoclonal MLANA-1761R unconjugated Recombinant Antibody
anti-Melan A (MLANA) antibodyMLANA 适用: 人, 小鼠, 大鼠 WB, IF, FACS, IHC, ISt, StM 宿主: 小鼠 Monoclonal M2-9E3 unconjugated
anti-Melan A (MLANA) antibodyMLANA 适用: 人, 马 IHC, ISt, StM 宿主: 小鼠 Monoclonal MLANA-1761R unconjugated
anti-Melan A (MLANA) (AA 48-118) antibodyMLANA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melan A (MLANA) (AA 1-118) antibodyMLANA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melan A (MLANA) antibodyMLANA 适用: 人, 小鼠, 大鼠, 犬 WB, IF, FACS, IHC, ISt, StM 宿主: 小鼠 Monoclonal A103 unconjugated
anti-Melan A (MLANA) antibodyMLANA 适用: 人, 小鼠, 大鼠, 犬 IHC, ISt, StM 宿主: 兔 Monoclonal MLANA-1409R unconjugated Recombinant Antibody
anti-Melan A (MLANA) antibodyMLANA 适用: 人, 小鼠, 大鼠, 犬 IHC, ISt, StM 宿主: 小鼠 Monoclonal rMLANA-788 unconjugated Recombinant Antibody
anti-Melan A (MLANA) antibodyMLANA 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-901M- unconjugated Recombinant Antibody
anti-Melan A (MLANA) (AA 48-118) antibodyMLANA 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2F3B7 unconjugated
-
-
应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology (formalin): 0.5-1 μg/mL. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM citrate buffer pH 6.0for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
-
说明
-
Positive Control: SK-MEL-13 and SK-MEL-19 Melanoma cell lines, Melanomas
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Protect from light
-
储存条件
- 4 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- MLANA (Melan A (MLANA))
-
别名
- MART-1
-
背景
-
Synonyms: Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA
Gene Symbol: MLANA
Tissue Expression: Melanocytes
-
分子量
- 20-22 kDa (doublet)
-
基因ID
- 2315
-
UniProt
- Q16655
抗原
-
