MMP2 抗体 (AA 444-575) (CF®740)
Quick Overview for MMP2 抗体 (AA 444-575) (CF®740) (ABIN7656706)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 444-575
-
原理
- MMP2 / Collagenase Type IV A (Tumor Metastasis Marker) (MMP2/1501), CF740 conjugate
-
产品特性
- This antibody recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- Recombinant human MMP2 protein fragment (aa444-575)
-
亚型
- IgG1
-
-
anti-Matrix Metalloproteinase 2 (MMP2) (AA 31-109) antibody
MMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 40-280) antibodyMMP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) antibodyMMP2 适用: 人 WB, IP, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 401-500) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B11E6 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (C-Term) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibodyMMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1E2 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal unconjugated
-
-
应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
-
说明
-
Positive Control: U-138 MG or U-87 MG cells. Placenta
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Protect from light
-
储存条件
- 4 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
-
别名
- Collagenase-Type-IV-A
-
背景
-
Synonyms: Type IV collagenase|CLG4A|Collagenase Type 4 alpha|Collagenase type IV A|Gelatinase A|Gelatinase alpha|Gelatinase neutrophil|Matrix metalloproteinase-2|MMP2|MONA|Neutrophil gelatinase|PEX|TBE-1
Gene Symbol: MMP2
-
分子量
- 72 kDa (Pro), 63 kDa (cleaved)
-
基因ID
- 4313
-
UniProt
- P08253
-
途径
- Activation of Innate immune Response
抗原
-
