Cytokeratin 5 抗体 (AA 316-590) (CF®488A)
Quick Overview for Cytokeratin 5 抗体 (AA 316-590) (CF®488A) (ABIN7656192)
抗原
See all Cytokeratin 5 (KRT5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 316-590
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原理
- Cytokeratin 5 (KRT5) (Basal, Myoepithelial & Mesothelial Cell Marker)(KRT5/3594), CF488A conjugate
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产品特性
- This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 316-590) of human Cytokeratin 5 (KRT5) protein
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亚型
- IgG1, kappa
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anti-Keratin 5 (KRT5) (AA 316-590) antibody
KRT5 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 10C11E6 unconjugated
anti-Keratin 5 (KRT5) antibodyKRT5 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Keratin 5 (KRT5) (AA 335-473) antibodyKRT5 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 316-590) antibodyKRT5 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal KRT5-3594 unconjugated
anti-Keratin 5 (KRT5) (AA 1-273) antibodyKRT5 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-Keratin 5 (KRT5) antibodyKRT5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 258-357) antibodyKRT5 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C8E4 unconjugated
anti-Keratin 5 (KRT5) (AA 331-430) antibodyKRT5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 163-471) antibodyKRT5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (C-Term) antibodyKRT5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: MCF-7 or HeLa cells. Human tonsil, esophagus or bladder tissue (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
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别名
- Keratin 5
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背景
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Synonyms: 58 kDa Cytokeratin, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, Type-II Cytoskeletal 5, Type-II keratin Kb5
Gene Symbol: KRT5
Tissue Expression: Epidermal cells
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分子量
- 58 kDa
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基因ID
- 3852
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UniProt
- P13647
抗原
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