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KRT14 抗体 (AA 351-472) (CF®647)

This anti-KRT14 antibody is a 小鼠 单克隆 antibody detecting KRT14 in IHC, FACS 和 IHC (fp). Suitable for 人, 大鼠, 小鼠 和 Pig.
产品编号 ABIN7655918
发货至: 中国

Quick Overview for KRT14 抗体 (AA 351-472) (CF®647) (ABIN7655918)

抗原

See all KRT14 抗体
KRT14 (Keratin 14 (KRT14))

适用

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人, 大鼠, 小鼠, Pig

宿主

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  • 2
小鼠

克隆类型

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单克隆

标记

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This KRT14 antibody is conjugated to CF®647

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

KRT14-2375
  • 抗原表位

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    AA 351-472

    原理

    Cytokeratin 14 (KRT14) (Squamous Cell Marker)(KRT14/2375), CF647 conjugate

    产品特性

    Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human KRT14 fragment (around aa351-472)

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: A431 or HeLa cells. Skin or Squamous Cell Carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    KRT14 (Keratin 14 (KRT14))

    别名

    Keratin 14

    背景

    Synonyms: CK-14, Dowling Meara, ebs3, ebs4, Epidermolysis Bullosa Simplex, k14, Keratin 14, Keratin Type I Cytoskeletal 14, Koebner, krt14, NFJ

    Gene Symbol: KRT14

    Tissue Expression: Epithelial cells

    分子量

    ~50 kDa

    基因ID

    3861

    UniProt

    P02533
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