IL7R 抗体 (AA 21-236) (CF®405S)
Quick Overview for IL7R 抗体 (AA 21-236) (CF®405S) (ABIN7655733)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-236
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原理
- CD127 / IL7R (Marker of T-Reg Cells)(IL7R/2751), CF405S conjugate
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产品特性
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R)
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亚型
- IgG2c, kappa
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应用备注
- ELISA: For coating, order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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说明
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Positive Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- IL7R (Interleukin 7 Receptor (IL7R))
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别名
- CD127
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背景
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Synonyms: CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor
Gene Symbol: IL7R
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分子量
- 52-72 kDa
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基因ID
- 3575
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UniProt
- P16871
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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