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CD51 抗体 (CF®405S)

This anti-CD51 antibody is a 小鼠 单克隆 antibody detecting CD51 in . Suitable for 人.
产品编号 ABIN7655394
发货至: 中国

Quick Overview for CD51 抗体 (CF®405S) (ABIN7655394)

抗原

See all CD51 (ITGAV) 抗体
CD51 (ITGAV) (Integrin alpha V (ITGAV))

适用

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宿主

  • 75
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小鼠

克隆类型

  • 86
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单克隆

标记

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This CD51 antibody is conjugated to CF®405S

应用范围

请咨询

克隆位点

ITGAV-1610
  • 原理

    CD51 / Integrin V(ITGAV/1610), CF405S conjugate

    产品特性

    Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length integrin alpha V beta 1 protein

    亚型

    IgG1, kappa
  • 应用备注

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    说明

    Positive Control: Squamous cells, A375M melanoma cells. A549 cells.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CD51 (ITGAV) (Integrin alpha V (ITGAV))

    别名

    CD51

    背景

    Synonyms: antigen identified by monoclonal antibody L230, CD 51, CD51, DKFZp686A08142, Integrin alpha five, integrin alpha V beta 3, Integrin alpha-5, integrin alpha-V, Integrin alpha-V light chain, integrin alphaVbeta3, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITAV_HUMAN, ITGAV, MSK 8, Msk8, Vitronectin receptor subunit alpha, VNRA, VTNR

    Gene Symbol: ITGAV

    分子量

    150-160 kDa under non-reducing conditions. Under reducing conditions, it is cleaved into 2 bands of about 125-130 kDa 20-25 kDa.

    基因ID

    3685

    UniProt

    P06756

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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