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Histone H1 抗体

This anti-Histone H1 antibody is a 兔 多克隆 antibody detecting Histone H1 in IF, IHC, FACS, WB 和 IHC (fp). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7655102
发货至: 中国

Quick Overview for Histone H1 抗体 (ABIN7655102)

抗原

See all Histone H1 抗体
Histone H1

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Histone H1 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 原理

    Histone H1 (Pan Nuclear Marker)(N/A)

    产品特性

    Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer, formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80 % of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human Histone H1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa, A-431, LNCap or Jurkat cells. Breast carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Histone H1

    背景

    Synonyms: HANP1, His1, HisC, HIST1, HIST1H1A, HIST1H1B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1T, Oocyte-specific histone H1, Testicular H1 histone

    Gene Symbol: H1

    分子量

    ~30 kDa

    基因ID

    3005
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