Recombinant CA 19-9 抗体 (CF®740)
Quick Overview for Recombinant CA 19-9 抗体 (CF®740) (ABIN7654296)
抗原
See all CA 19-9 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CA19-9/Sialyl Lewisa (GI Tumor Marker) (CA19.9/1390R), CF740 conjugate
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产品特性
- CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Purified human CA19-9 protein
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亚型
- IgG, kappa
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anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibody
CA 19-9 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 121SLE unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 ELISA, FACS, IHC (p), WB, IHC (fro) 宿主: 小鼠 Monoclonal 121SLE unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 IHC, StM 宿主: 兔 Monoclonal CA19-9-1390R unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 IHC, FACS, IF, ISt 宿主: 小鼠 Monoclonal SPM588 unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal 121SLE unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence 0.5-1 μg/mL Immunohistology (formalin) 5-10 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Stomach or Colon Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
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别名
- CA19-9
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背景
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Synonyms: CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a
Gene Symbol: Not Known
Tissue Expression: Epithelial cells
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分子量
- >400 kDa
抗原
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