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CA 19-9 抗体

CA 19-9 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal 121SLE unconjugated
产品编号 ABIN6941326
发货至: 中国
  • 抗原 See all CA 19-9 抗体
    CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
    适用
    • 34
    • 1
    • 1
    宿主
    • 21
    • 15
    小鼠
    克隆类型
    • 32
    • 3
    单克隆
    标记
    • 19
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CA 19-9 antibody is un-conjugated
    应用范围
    • 19
    • 15
    • 15
    • 13
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
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    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    CA19-9, a carbohydrate epitope expressed on a high MW (400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
    免疫原
    Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient (0Le).
    克隆位点
    121SLE
    亚型
    IgM kappa
    Top Product
    Discover our top product CA 19-9 Primary Antibody
  • 应用备注

    Positive Control: Stomach or Colon Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
    别名
    CA19-9/Sialyl Lewisa (GI Tumor Marker) (CA 19-9 产品)
    分子量
    >400kDa
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