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Recombinant FTL 抗体 (AA 38-165) (CF®594)

This anti-FTL antibody is a 兔 单克隆 antibody detecting FTL in WB, IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7654021
发货至: 中国

Quick Overview for Recombinant FTL 抗体 (AA 38-165) (CF®594) (ABIN7654021)

抗原

See all FTL 抗体
FTL (Ferritin, Light Polypeptide (FTL))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 105
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单克隆

标记

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This FTL antibody is conjugated to CF®594

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

FTL-2338R
  • 抗原表位

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    AA 38-165

    原理

    Ferritin, Light Chain (FTL) (Microglia Marker) (FTL/2338R), CF594 conjugate

    产品特性

    Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human FTL protein fragment (around aa 38-165)

    亚型

    IgG
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.5-1.0 μg/mL for 30 minutes at RT. Western Blotting 0.5-2 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    FTL (Ferritin, Light Polypeptide (FTL))

    别名

    Ferritin, Light Chain

    背景

    Synonyms: Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

    Gene Symbol: FTL

    分子量

    19-25 kDa

    基因ID

    2512

    UniProt

    P02792

    途径

    Transition Metal Ion Homeostasis
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