FTH1 抗体 (AA 58-180) (CF®647)
Quick Overview for FTH1 抗体 (AA 58-180) (CF®647) (ABIN7653991)
抗原
See all FTH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 58-180
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原理
- Ferritin, Heavy Chain (FTH) (Microglia Marker)(FTH/2081), CF647 conjugate
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产品特性
- Mammalian ferritins consist of 24 subunits made up of 2 types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidationof FeI(II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe(III). The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of aging-related cataracts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human FTH1 protein fragment (around aa 58-180)
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亚型
- IgG2a, kappa
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anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibody
FTH1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) antibodyFTH1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-181) antibodyFTH1 适用: Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (C-Term) antibodyVerified FTH1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibodyFTH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-100) antibodyFTH1 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibodyFTH1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 58-180) antibodyFTH1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal FTH-2081 unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (C-Term) antibodyFTH1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) antibodyFTH1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
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别名
- Ferritin, Heavy Chain
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背景
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Synonyms: Apoferritin, Cell proliferation-inducing gene 15 protein, Ferritin H subunit, Ferritin heavy chain, FHC, FRIH, FTH1, FTHL6, Iron overload autosomal dominant, PIG15, Placenta immunoregulatory factor, Proliferation inducing gene 15 protein (PLIF)
Gene Symbol: FTH1
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分子量
- 21 kDa
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基因ID
- 2495
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UniProt
- P02794
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途径
- Transition Metal Ion Homeostasis
抗原
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