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ESR2 抗体 (C-Term) (CF®740)

Name: ESR2 抗体 (C-Term) (CF®740)
SKU: ABIN7653849
Availability: OutOfStock

This anti-ESR2 antibody is a 小鼠单克隆 antibody detecting ESR2 in IHC, FACS 和 IHC (fp). Suitable for 人.

产品编号 ABIN7653849

发货至: 中国

Quick Overview for ESR2 抗体 (C-Term) (CF®740) (ABIN7653849)

抗原

See all ESR2 抗体

ESR2 (Estrogen Receptor 2 (ESR2))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This ESR2 antibody is conjugated to CF®740

应用范围

Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

ESR2-686

Discover our top product ESR2 Primary Antibody

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C-Term

原理

Estrogen Receptor beta 1(ESR2/686), CF740 conjugate

产品特性

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

C-terminus fragment of recombinant human estrogen receptor beta protein

亚型

IgG2a
anti-Estrogen Receptor 2 (ESR2) (C-Term) antibody
ESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ERb455 unconjugated

anti-Estrogen Receptor 2 (ESR2) (N-Term) antibody
ESR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 2 (ESR2) (C-Term) antibody
ESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal ERb455 unconjugated

anti-Estrogen Receptor 2 (ESR2) (AA 201-300) antibody
ESR2 适用: 人, 小鼠, 大鼠, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 2 (ESR2) (AA 46-530) antibody
ESR2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 2 (ESR2) (AA 211-240) antibody
ESR2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41114 unconjugated

anti-Estrogen Receptor 2 (ESR2) (AA 417-428) antibody
Verified ESR2 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Estrogen Receptor 2 (ESR2) (AA 22-121) antibody
ESR2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F3 unconjugated

anti-Estrogen Receptor 2 (ESR2) (pSer105) antibody
ESR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 2 (ESR2) (AA 1-280) antibody
ESR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology formalin-fixed 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

说明

Positive Control: MCF-7 Cells. Ovarian, Breast, Bladder, Gastric or Salivary carcinoma

限制

仅限研究用
状态

Liquid

浓度

0.1 mg/mL

缓冲液

PBS, 0.1 % rBSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Protect from light

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

ESR2 (Estrogen Receptor 2 (ESR2))

别名

Estrogen Receptor Beta 1

背景

Synonyms: Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 (ER beta), estrogen receptor beta 4
Gene Symbol: ESR2

分子量

53-59 kDa

基因ID

2100

UniProt

Q92731

途径

Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling