SATB1 抗体 (AA 671-764)
Quick Overview for SATB1 抗体 (AA 671-764) (ABIN732008)
抗原
See all SATB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 671-764
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from mouse SATB1
-
亚型
- IgG
-
-
anti-SATB Homeobox 1 (SATB1) (AA 484-763) antibody
SATB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (C-Term) antibodySATB1 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (pSer47) antibodySATB1 适用: 人, 小鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (AA 1-763) antibodySATB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (Internal Region) antibodyVerified SATB1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) antibodySATB1 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 3548D4_2a unconjugated
anti-SATB Homeobox 1 (SATB1) antibodySATB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (AA 484-763) antibodySATB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (AA 611-660) antibodySATB1 适用: 人, 大鼠, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SATB Homeobox 1 (SATB1) (N-Term) antibodySATB1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- SATB1 (SATB Homeobox 1 (SATB1))
-
别名
- SATB1
-
背景
-
Synonyms: AW413156, 2610306G12Rik, DNA-binding protein SATB1, Special AT-rich sequence-binding protein 1, Satb1
Background: Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis (By similarity). Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma. Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes.
-
基因ID
- 20230
-
UniProt
- Q60611
-
途径
- Caspase Cascade in Apoptosis, Activated T Cell Proliferation
抗原
-
