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ENO2/NSE 抗体 (AA 416-433) (CF®594)

This anti-ENO2/NSE antibody is a 小鼠 单克隆 antibody detecting ENO2/NSE in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7653508
发货至: 中国
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Quick Overview for ENO2/NSE 抗体 (AA 416-433) (CF®594) (ABIN7653508)

抗原

See all ENO2/NSE (ENO2) 抗体
ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ENO2/NSE antibody is conjugated to CF®594

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

NSE-P2
  • 抗原表位

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    AA 416-433

    原理

    NSE gamma (Neuron Specific Enolase, gamma) (Neuroendocrine Marker)(NSE-P2), CF594 conjugate

    产品特性

    This monoclonal antibody recognizes a protein of about 50 kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    A synthetic peptide of human NSE gamma (around aa416-433)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HepG2, SH-SY-5Y, HeLa or Y79 cells. Pancreas, Cerebellum or Pheochromocytoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

    别名

    NSE-Gamma

    背景

    Synonyms: 2-phospho-D-glycerate hydrolyase, ENO2, ENOG, Enolase 2 gamma neuronal, Enolase2, Gamma-enolase, Neural enolase, Neuron specific gamma enolase, Neuron-specific enolase, NSE

    Gene Symbol: ENO2

    Tissue Expression: Neurons

    分子量

    ~50 kDa

    基因ID

    2026

    UniProt

    P09104
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