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Recombinant Elastase 3B 抗体 (AA 82-238) (CF®405S)

This anti-Elastase 3B antibody is a 小鼠 单克隆 antibody detecting Elastase 3B in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7653378
发货至: 中国

Quick Overview for Recombinant Elastase 3B 抗体 (AA 82-238) (CF®405S) (ABIN7653378)

抗原

See all Elastase 3B (ELA3B) 抗体
Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

抗体类型

Recombinant Antibody

适用

  • 122
  • 25
  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 79
  • 58
小鼠

克隆类型

  • 103
  • 34
单克隆

标记

  • 56
  • 21
  • 9
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 1
  • 1
  • 1
  • 1
This Elastase 3B antibody is conjugated to CF®405S

应用范围

  • 81
  • 67
  • 55
  • 42
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  • 36
  • 31
  • 15
  • 11
  • 8
  • 5
  • 4
  • 4
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

RCELA3B-1811
  • 抗原表位

    • 95
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 82-238

    原理

    CELA3B / ELA3B (Pancreatic Function Marker)(rCELA3B/1811), CF405S conjugate

    产品特性

    This MAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human CELA3B protein fragment (around aa 82-238)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Panc-28 or PANC1 cells. Human Pancreas.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

    别名

    CELA3B

    背景

    Synonyms: Chymotrypsin like elastase family member 3B (CELA3B), ELA3B, Elastase IIIB, Protease E

    Gene Symbol: CELA3B

    分子量

    17 kDa

    基因ID

    23436

    UniProt

    P08861
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