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Dystrophin 抗体 (AA 114-263) (CF®568)

Name: Dystrophin 抗体 (AA 114-263) (CF®568)
SKU: ABIN7653321
Availability: OutOfStock

This anti-Dystrophin antibody is a 小鼠单克隆 antibody detecting Dystrophin in IHC 和 IHC (fp). Suitable for 人.

产品编号 ABIN7653321

发货至: 中国

Quick Overview for Dystrophin 抗体 (AA 114-263) (CF®568) (ABIN7653321)

抗原

See all Dystrophin (DMD) 抗体

Dystrophin (DMD)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Dystrophin antibody is conjugated to CF®568

应用范围

Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

DMD-3243

Discover our top product DMD Primary Antibody

抗原表位
55

8

4

4

3

2

2

1

1

1

1
AA 114-263

原理

Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy)(DMD/3243), CF568 conjugate

产品特性

Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2. 4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0. 002 % of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

A recombinant fragment (around aa 114-263) of human DMD protein

亚型

IgG1, kappa
anti-Dystrophin (DMD) (AA 346-635) antibody
DMD 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Dystrophin (DMD) antibody
DMD 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Dystrophin (DMD) (AA 1-635) antibody
DMD 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A11 unconjugated

anti-Dystrophin (DMD) (AA 114-263) antibody
DMD 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal DMD-3242 unconjugated

anti-Dystrophin (DMD) (AA 3076-3404) antibody
DMD 适用: 人, 小鼠, 大鼠 IHC, WB, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

anti-Dystrophin (DMD) (AA 3048-3328) antibody
DMD 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dystrophin (DMD) (AA 114-263) antibody
DMD 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal DMD-3241 unconjugated

anti-Dystrophin (DMD) (AA 114-263) antibody
DMD 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal DMD-3245 unconjugated

anti-Dystrophin (DMD) (AA 253-597) antibody
DMD 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dystrophin (DMD) (AA 3400-3558) antibody
DMD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

Positive Control: Human skeletal muscle and heart muscle tissues (IHC).

限制

仅限研究用
状态

Liquid

浓度

0.1 mg/mL

缓冲液

PBS, 0.1 % BSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Protect from light

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

Dystrophin (DMD)

别名

Dystrophin

背景

Synonyms: BMD, CMD3B, Duchenne muscular dystrophy (DMD), Dystrophin, Muscular dystrophy Duchenne and Becker types
Gene Symbol: DMD
Tissue Expression: Muscle

分子量

427 kDa

基因ID

1756

UniProt

P11532

途径

Skeletal Muscle Fiber Development