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DNMT1 抗体 (AA 767-912)

This anti-DNMT1 antibody is a 小鼠 单克隆 antibody detecting DNMT1 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7653206
发货至: 中国

Quick Overview for DNMT1 抗体 (AA 767-912) (ABIN7653206)

抗原

See all DNMT1 抗体
DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

适用

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宿主

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小鼠

克隆类型

  • 131
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单克隆

标记

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This DNMT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

DNMT1-2061
  • 抗原表位

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    AA 767-912

    原理

    DNMT1 / DNA Methyltransferase 1(DNMT1/2061)

    产品特性

    This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human DNMT1 protein fragment (around aa 767-912)

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Raji cells. Tonsil or Placenta.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

    别名

    DNA Methyltransferase 1

    背景

    Synonyms: ADCADN, AIM, CXXC-type zinc finger protein 9, CXXC9, DNA methyltransferase 1 (DNMT1), HSN1E, MCMT, Met1, MommeD2

    Gene Symbol: DNMT1

    分子量

    184 kDa

    基因ID

    1786

    UniProt

    P26358

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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