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CD35 抗体 (CF®594)

This anti-CD35 antibody is a 小鼠 单克隆 antibody detecting CD35 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7652673
发货至: 中国

Quick Overview for CD35 抗体 (CF®594) (ABIN7652673)

抗原

See all CD35 (CR1) 抗体
CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD35 antibody is conjugated to CF®594

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

To5
  • 原理

    CD35 / CR1 (Follicular Dendritic Cell Marker)(To5), CF594 conjugate

    产品特性

    Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21 /CD35 /CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human CR1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Follicular dendritic cells (FDC) in tonsil

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

    别名

    CD35

    背景

    Synonyms: C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen

    Gene Symbol: CR1

    Tissue Expression: Antigen presenting cells

    分子量

    210-220 kDa

    基因ID

    1378

    UniProt

    P17927

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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