CD21 抗体 (CF®740)
Quick Overview for CD21 抗体 (CF®740) (ABIN7652534)
抗原
See all CD21 (CR2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD21(FR5A10), CF740 conjugate
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产品特性
- Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2)/CD21. Its epitope is located in 5-8 short consensus repeats (SCRs). This MAb is highly specific to CR2 and shows no cross-reaction with CR1. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. MAb FR5A10 can be used for EBV receptor studies, interactions between B and T cells especially through CD23, human complement receptor (CR2) studies and IFN-alpha receptor studies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Raji cells
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亚型
- IgG1, kappa
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anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibody
CR2 适用: 人 FACS, IHC, WB, IF, ELISA, StM, Coat 宿主: 小鼠 Monoclonal CR2-2754 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Monoclonal 16F10 unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 300-590) antibodyCR2 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 740-964) antibodyCR2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2D2H6 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 981-1092) antibodyCR2 适用: 人, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibodyCR2 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal CR2-3124R unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 44-196) antibodyCR2 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal CR2-1952 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, Pig, Cow, 犬 FACS, IHC (fro) 宿主: 小鼠 Monoclonal LT21 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Tonsil
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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别名
- CD21
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背景
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Synonyms: CD21, Complement C3d receptor (C3DR), Complement Receptor type 2 (CR2), CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, SLEB9
Gene Symbol: CR2
Tissue Expression: Antigen presenting cells|B-cells|Lymphocytes
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分子量
- 140 kDa
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基因ID
- 1380
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UniProt
- P20023
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途径
- Complement System
抗原
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