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CD99 抗体 (CF®405S)

This anti-CD99 antibody is a 兔 多克隆 antibody detecting CD99 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7652316
发货至: 中国

Quick Overview for CD99 抗体 (CF®405S) (ABIN7652316)

抗原

See all CD99 抗体
CD99

适用

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宿主

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克隆类型

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多克隆

标记

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This CD99 antibody is conjugated to CF®405S

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 原理

    CD99 / MIC2 (Ewing's Sarcoma Marker), CF405S conjugate

    产品特性

    Recognizes a sialoglycoprotein of 27-32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32). Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis. CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human MIC2 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: MOLT-4 cells. Pancreas or Ewing sarcoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CD99

    别名

    CD99

    背景

    Synonyms: 12E7, E2 antigen, MIC 2X, MIC 2Y, MIC2, Protein MIC2, Surface antigen MIC2, T-cell surface glycoprotein E2

    Gene Symbol: CD99

    Tissue Expression: Lymphocytes|Ovary|Pancreatic islet cells|T-cells|Testis

    分子量

    27-32 kDa

    基因ID

    4267

    UniProt

    P14209
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