CD79b 抗体 (AA 29-159) (CF®488A)
Quick Overview for CD79b 抗体 (AA 29-159) (CF®488A) (ABIN7652001)
抗原
See all CD79b (CD79B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 29-159
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原理
- CD79b (B-Cell Marker) (IGB/1844), CF488A conjugate
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产品特性
- CD79 (also designated Ig α/Igβ) is a heterodimer composed of α chains, designated CD79A or MB-1, andβ chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human CD79b protein fragment (around aa 29-159)
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亚型
- IgG1, kappa
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
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别名
- CD79b
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背景
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Synonyms: AGM6, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, B29/Ig-beta/CD79b, CD79b, Ig-beta, IGB, Immunoglobulin-associated B29 protein
Gene Symbol: CD79B
Tissue Expression: NK cells|T-cells
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分子量
- 39 kDa
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基因ID
- 974
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UniProt
- P40259
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途径
- BCR Signaling
抗原
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