CD72 抗体 (Biotin)
Quick Overview for CD72 抗体 (Biotin) (ABIN7651961)
抗原
See all CD72 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- CD72 (B Cell Marker)(BU40), Biotin conjugate
-
产品特性
- The C-type lectin superfamily member CD72 is a cell surface negative regulator of B cell activation from the pro-B through the mature B cell stage. CD72 serves as a receptor for CD5. The human CD72 gene encodes a transmembrane glycoprotein that contains an immunoreceptor tyrosine-based inhibition motif (ITIM). Upon tyrosine phosphorylation, the CD72 ITIM recruits SH2-containing phosphatases such as SHP-1, resulting in downregulation of cell activation. CD72-/- mice contain hyperproliferative B cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- HF B1 plasmacytoid cell line.
-
亚型
- IgG2a, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
Positive Control: K562 cel lysate. Tonsil or Lymph Node.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- CD72 (CD72 Molecule (CD72))
-
别名
- CD72
-
背景
-
Synonyms: B cell differentiation antigen CD72, CD72b, CD72c, Ly-19, Ly-32, Ly-m19, LYB2, Lymphocyte antigen 32
Gene Symbol: CD72
Tissue Expression: B-cells
-
分子量
- 45 kDa
-
基因ID
- 971
-
UniProt
- P21854
-
途径
- BCR Signaling
抗原
-