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CD72 抗体 (CF®640R)

The 小鼠 单克隆 anti-CD72 antibody is suitable to detect CD72 in samples from 人. It has been validated for IHC 和 IHC (fp).
产品编号 ABIN7651955
发货至: 中国
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Room 801-803
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Quick Overview for CD72 抗体 (CF®640R) (ABIN7651955)

抗原

See all CD72 抗体
CD72 (CD72 Molecule (CD72))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD72 antibody is conjugated to CF®640R

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

BU40
  • 原理

    CD72 (B Cell Marker)(BU40), CF640R conjugate

    产品特性

    The C-type lectin superfamily member CD72 is a cell surface negative regulator of B cell activation from the pro-B through the mature B cell stage. CD72 serves as a receptor for CD5. The human CD72 gene encodes a transmembrane glycoprotein that contains an immunoreceptor tyrosine-based inhibition motif (ITIM). Upon tyrosine phosphorylation, the CD72 ITIM recruits SH2-containing phosphatases such as SHP-1, resulting in downregulation of cell activation. CD72-/- mice contain hyperproliferative B cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    HF B1 plasmacytoid cell line.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: K562 cel lysate. Tonsil or Lymph Node.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CD72 (CD72 Molecule (CD72))

    别名

    CD72

    背景

    Synonyms: B cell differentiation antigen CD72, CD72b, CD72c, Ly-19, Ly-32, Ly-m19, LYB2, Lymphocyte antigen 32

    Gene Symbol: CD72

    Tissue Expression: B-cells

    分子量

    45 kDa

    基因ID

    971

    UniProt

    P21854

    途径

    BCR Signaling
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