CD36 抗体 (CF®488A)
Quick Overview for CD36 抗体 (CF®488A) (ABIN7651315)
抗原
See all CD36 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD36 (Platelet & Microvessel Marker)(GPIIIb/1654), CF488A conjugate
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产品特性
- Recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4 % of Japanese and East Asia population lack CD36. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human GPIIIb protein
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亚型
- IgG2a, kappa
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anti-CD36 (CD36) (Extracellular Domain) antibody
CD36 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 99-114) antibodyCD36 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (C-Term) antibodyCD36 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (N-Term) antibodyCD36 适用: 人, 小鼠, 大鼠, 犬, Pig, 兔, Cow, 山羊, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 213-242) antibodyCD36 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 51-150) antibodyCD36 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) antibody (FITC)CD36 适用: 人 FACS 宿主: 小鼠 Monoclonal CB38 FITC
anti-CD36 (CD36) (AA 30-130) antibodyCD36 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 5B6F5 unconjugated
anti-CD36 (CD36) (AA 30-130) antibodyCD36 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5B6B2 unconjugated
anti-CD36 (CD36) (N-Term) antibodyCD36 适用: 人, 大鼠, 犬, Pig, 兔, Cow, 山羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: HEL or U937 cells. Platelets, monocytes, macrophages, microvascular endothelial cells in a tonsil.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD36
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别名
- CD36
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背景
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Synonyms: Adipocyte membrane protein, CHDS7, Collagen receptor, platelet, fatty acid translocase (FAT), Fatty acid transport protein, glycoprotein iiib (GP IIIb), PAS IV, PAS-4, pas4 protein, platelet collagen receptor, Platelet glycoprotein 4, scarb3, Scavenger receptor class B member 3, thrombospondin receptor
Gene Symbol: CD36
Tissue Expression: Platelets|Erythrocyte precursors|Mammary gland|Microvascular endothelial cells|Monocytes/macrophages
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分子量
- 80-90 kDa
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基因ID
- 948
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UniProt
- P16671
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途径
- TLR signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins
抗原
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