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PD-L1 抗体 (AA 39-191) (CF®405S)

This anti-PD-L1 antibody is a 小鼠单克隆 antibody detecting PD-L1 in FACS 和 IF. Suitable for 人.

产品编号 ABIN7651046

发货至: 中国

Quick Overview for PD-L1 抗体 (AA 39-191) (CF®405S) (ABIN7651046)

抗原

See all PD-L1 抗体

PD-L1 (CD274 (PD-L1))

适用

225
165
74
6
6
6
5
1
1

人

宿主

小鼠

克隆类型

单克隆

标记

This PD-L1 antibody is conjugated to CF®405S

应用范围

185
159
81
78
40
32
32
28
21
15
11
11
9
7
7
5
3
3
2
2
2
1
1
1
1
1
1
1

Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

PDL1-2743

Discover our top product PD-L1 Primary Antibody

抗原表位
31

29

16

15

10

8

8

7

7

6

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 39-191

原理

PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target)(PDL1/2743), CF405S conjugate

产品特性

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

免疫原

Recombinant fragment of human CD274 protein (around aa 39-191)

亚型

IgG2b, kappa
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 适用: 人 WB, FACS, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 适用: 人, 小鼠 WB, ELISA, Coat 宿主: 小鼠 Monoclonal PDL1-2744 unconjugated

应用备注

ELISA: For coating, order antibody without BSA, Flow cytometry: 1-2 μg/mL, Immunofluorescence: 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

说明

Positive Control: Heart, Placenta, Spleen or Tonsil (IHC). Jurkat cells (IF/FACS).

限制

仅限研究用
状态

Liquid

浓度

0.1 mg/mL

缓冲液

PBS, 0.1 % BSA, 0.05 % azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Protect from light

储存条件

4 °C

储存方法

Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light

有效期

24 months
抗原

PD-L1 (CD274 (PD-L1))

别名

B7-H1

背景

Synonyms: B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1
Gene Symbol: CD274

分子量

37-50 kDa

基因ID

29126

UniProt

Q9NZQ7

途径

Cancer Immune Checkpoints

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