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Recombinant DC-SIGN/CD209 抗体 (Biotin)

This anti-DC-SIGN/CD209 antibody is a 兔 单克隆 antibody detecting DC-SIGN/CD209 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7650993
发货至: 中国

Quick Overview for Recombinant DC-SIGN/CD209 抗体 (Biotin) (ABIN7650993)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This DC-SIGN/CD209 antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

C209-2749R
  • 原理

    CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells)(C209/2749R), Biotin conjugate

    产品特性

    DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human CD209 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    CD209

    背景

    Synonyms: CD209, CDSIGN, CIRE, CLEC4L, DC-SIGN, DC-SIGN1, DCSIGN, Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1, HIV GP120 Binding Protein, SIGN-R1, SIGNR5

    Gene Symbol: CD209

    Tissue Expression: Antigen presenting cells|Monocytes/macrophages|Myeloid cells

    分子量

    45 kDa

    基因ID

    30835

    UniProt

    Q9NNX6
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