Recombinant DC-SIGN/CD209 抗体 (CF®640R)
Quick Overview for Recombinant DC-SIGN/CD209 抗体 (CF®640R) (ABIN7650981)
抗原
See all DC-SIGN/CD209 (CD209) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells)(rC209/1781), CF640R conjugate
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产品特性
- DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human CD209 protein fragment
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亚型
- IgG1, kappa
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anti-CD209 (CD209) (AA 70-404) antibody
CD209 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal C209-1781 unconjugated
anti-CD209 (CD209) (AA 270-404) antibodyCD209 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5C2A6 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, IP, IHC (p) 宿主: 大鼠 Monoclonal h209 unconjugated
anti-CD209 (CD209) (AA 1-404) antibodyCD209 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD209 (CD209) (AA 115-238) antibodyCD209 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) (AA 271-380) antibodyCD209 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal rC209-1781 unconjugated Recombinant Antibody
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, ICC 宿主: 小鼠 Monoclonal UW60-1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- DC-SIGN/CD209 (CD209) (CD209)
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别名
- CD209
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背景
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Synonyms: CD209, CDSIGN, CIRE, CLEC4L, DC-SIGN, DC-SIGN1, DCSIGN, Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1, HIV GP120 Binding Protein, SIGN-R1, SIGNR5
Gene Symbol: CD209
Tissue Expression: Antigen presenting cells|Monocytes/macrophages|Myeloid cells
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分子量
- 45 kDa
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基因ID
- 30835
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UniProt
- Q9NNX6
抗原
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