CDX2 抗体
Quick Overview for CDX2 抗体 (ABIN7650763)
抗原
See all CDX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)(CDX2/2214)
-
产品特性
- The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
免疫原
- Recombinant human full-length CDX2 protein
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
Positive Control: HT29 cells. Colon Carcinoma.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, no BSA, no azide
-
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
-
Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
-
有效期
- 24 months
-
-
- CDX2 (Caudal Type Homeobox 2 (CDX2))
-
别名
- Caudal Type Homeobox 2
-
背景
-
Synonyms: Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2
Gene Symbol: CDX2
Tissue Expression: Intestine
-
分子量
- 40 kDa
-
基因ID
- 1045
-
UniProt
- Q99626
-
途径
- Peptide Hormone Metabolism, Stem Cell Maintenance
抗原
-