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CDX2 抗体

This anti-CDX2 antibody is a 小鼠 单克隆 antibody detecting CDX2 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7650759
发货至: 中国

Quick Overview for CDX2 抗体 (ABIN7650759)

抗原

See all CDX2 抗体
CDX2 (Caudal Type Homeobox 2 (CDX2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CDX2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CDX2-2214
  • 原理

    CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)(CDX2/2214)

    产品特性

    The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19, 000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length CDX2 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HT29 cells. Colon Carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS, 0.05 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    CDX2 (Caudal Type Homeobox 2 (CDX2))

    别名

    Caudal Type Homeobox 2

    背景

    Synonyms: Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2

    Gene Symbol: CDX2

    Tissue Expression: Intestine

    分子量

    40 kDa

    基因ID

    1045

    UniProt

    Q99626

    途径

    Peptide Hormone Metabolism, Stem Cell Maintenance
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