CTNND1 抗体 (CF®740)
Quick Overview for CTNND1 抗体 (CF®740) (ABIN7650595)
抗原
See all CTNND1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - Catenin, delta-1 (CTNND1) (pTyr96) (25a), CF740 conjugate
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产品特性
 - Delta 1 catenin, also known as p120 catenin, is a tyrosine kinase substrate that is phosphorylated in Src transformed cells or in response to growth factor stimulation. Like beta- and gamma-catenin, p120 Catenin directly associates with the cytoplasmic C-terminus of E-Cadherin via its Arm domain and may similarly interact with other cadherins. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
 - Mouse p120 Catenin (pY96)
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亚型
 - IgG1, kappa
 
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应用备注
 - For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Carcinoma
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 0.1 mg/mL
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缓冲液
 - PBS, 0.1 % rBSA, 0.05 % azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Protect from light
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储存条件
 - 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
 - 24 months
 
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- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
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别名
 - Catenin, Delta-1
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背景
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Synonyms: Delta 1 cadherin, Catenin delta-1, Cadherin-associated Src substrate (CAS), Catenin (cadherin associated protein) delta 1, CTNND1, p120 catenin
Gene Symbol: CTNND1
Tissue Expression: Epithelial cells
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分子量
 - 120 kDa
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基因ID
 - 1500
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途径
 - EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
 
抗原
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