CTNNA1 抗体 (CF®740)
Quick Overview for CTNNA1 抗体 (CF®740) (ABIN7650594)
抗原
See all CTNNA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Catenin, alpha-1 (CTNNA1) (1G5), CF740 conjugate
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产品特性
- Alpha-E-catenin (also known as Alpha-1 catenin) is part of the catenin family, a large family of Ca2 -dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-E-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-E-catenin forms a heterodimer with beta-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-E-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human alpha catenin fusion protein
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亚型
- IgG1
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anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (C-Term) antibody
CTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 637-906) antibodyCTNNA1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) antibodyCTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 143-292) antibodyCTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (Internal Region) antibodyVerified CTNNA1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 371-574) antibodyCTNNA1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8B6C1 unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 2-228) antibodyCTNNA1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 1-288) antibodyCTNNA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 152-250) antibodyCTNNA1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) antibodyCTNNA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HeLa, A431 or MCF-7 Cells.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
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别名
- Alpha-1 catenin
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背景
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Synonyms: Alpha-E-catenin, Alpha-1 catenin, Cadherin-associated protein, Catenin alpha-1, CTNNA1
Gene Symbol: CTNNA1
Tissue Expression: Epithelial cells
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分子量
- 102 kDa
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基因ID
- 1495
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UniProt
- P35221
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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