CTNNA1 抗体 (AA 143-292)
(2 references)-
- 抗原 See all CTNNA1 抗体
- CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
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抗原表位
- AA 143-292
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTNNA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 原理
- Rabbit IgG polyclonal antibody for Catenin alpha-1(CTNNA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Catenin alpha-1(CTNNA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: catenin (cadherin-associated protein), alpha 1, 102 kDa
Protein Name: Catenin alpha-1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human CTNNA1 recombinant protein (Position: D143-D292). Human CTNNA1 shares 98% amino acid (aa) sequence identity with mouse CTNNA1.
- 亚型
- IgG
- Top Product
- Discover our top product CTNNA1 Primary Antibody
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anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (C-Term) antibody
CTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 637-906) antibodyCTNNA1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) antibodyCTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (Internal Region) antibodyVerified CTNNA1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 371-574) antibodyCTNNA1 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8B6C1 unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 2-228) antibodyCTNNA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 1-288) antibodyCTNNA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 152-250) antibodyCTNNA1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (pSer641) antibodyCTNNA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) antibodyCTNNA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for CTNNA1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
: "Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma." in: World journal of gastroenterology, Vol. 10, Issue 22, pp. 3235-9, (2005) (PubMed).
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: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
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- 抗原
- CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
- 别名
- CTNNA1 (CTNNA1 产品)
- 别名
- CAP102 antibody, 2010010M04Rik antibody, AA517462 antibody, AI988031 antibody, Catna1 antibody, CG17947 antibody, CT39986 antibody, Dalpha-Cat antibody, Dalpha-cat antibody, DalphaC antibody, Dalphacat antibody, Dmcatp antibody, Dmel\\CG17947 antibody, a-Cat antibody, a-cat antibody, alpha-CAT antibody, alpha-cat antibody, alpha-catenin antibody, alpha-ctn antibody, alphaCAT antibody, alphaCat antibody, alphacat antibody, Alpha-Cat antibody, dgri_GLEANR_3829 antibody, DgriGH19548 antibody, GH19548 antibody, ctnna antibody, cap102 antibody, catna1 antibody, ctnna1 antibody, catenin alpha 1 antibody, catenin (cadherin associated protein), alpha 1 antibody, alpha Catenin antibody, catenin alpha-1 antibody, catenin (cadherin-associated protein), alpha 1 antibody, catenin alpha 1 S homeolog antibody, CTNNA1 antibody, Ctnna1 antibody, alpha-Cat antibody, Dgri\alpha-Cat antibody, Tsp_10127 antibody, ctnna1 antibody, ctnna1.S antibody
- 背景
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CTNNA1, also known as Catenin alpha-1 or Catenin (cadherin-associated protein), alpha 1, is a protein that in humans is encoded by the CTNNA1 gene. It is mapped to 5q31.2. When surface epithelium CTNNA1 was ablated, hair follicle development was blocked and epidermal morphogenesis was dramatically affected, with defects in adherens junction formation, intercellular adhesion, and epithelial polarity. In vitro, CTNNA1 null keratinocytes were poorly contact inhibited and grew rapidly. These differences were not dependent upon intercellular adhesion and were in marked contrast to keratinocytes conditionally null for another essential intercellular adhesion protein, desmoplakin Knockout keratinocytes exhibited sustained activation of the Ras-MAPK cascade due to aberrations in growth factor responses. It is concluded that features of precancerous lesions often attributed to defects in cell cycle regulatory genes can be generated by compromising the function of CTNNA1.
Synonyms: alpha catenin antibody|alpha E catenin antibody|Alpha E-catenin antibody|alphaE catenin antibody|Cadherin associated protein 102 kDa antibody|Cadherin associated protein antibody|Cadherin-associated protein antibody|CAP 102 antibody|CAP102 antibody|Catenin (cadherin associated protein) alpha 1 102 kDa antibody|Catenin (cadherin associated protein), alpha 1, 102 kDa antibody|Catenin alpha 1 antibody|Catenin alpha-1 antibody|CTNA1_HUMAN antibody|CTNNA 1 antibody|CTNNA1 antibody|FLJ36832 antibody|FLJ52416 antibody|NY REN 13 antigen antibody|OTTHUMP00000224141 antibody|OTTHUMP00000224147 antibody|Renal carcinoma antigen NY REN 13 antibody|Renal carcinoma antigen NY-REN-13 antibody - 基因ID
- 1495
- UniProt
- P35221
- 途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
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