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Calpastatin 抗体 (Biotin)

This anti-Calpastatin antibody is a 小鼠 单克隆 antibody detecting Calpastatin in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7650450
发货至: 中国

Quick Overview for Calpastatin 抗体 (Biotin) (ABIN7650450)

抗原

See all Calpastatin (CAST) 抗体
Calpastatin (CAST)

适用

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宿主

  • 43
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小鼠

克隆类型

  • 46
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单克隆

标记

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This Calpastatin antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CAST-1550
  • 原理

    Calpastatin(CAST/1550), Biotin conjugate

    产品特性

    Calpastatin is an inhibitor of calpain (calcium-activated intracellular cysteine protease). Calpastatin regulates calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpastatin co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human CAST protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HeLa cells. Esophagus or Small Intestine.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Calpastatin (CAST)

    别名

    Calpastatin

    背景

    Synonyms: Calpastatin, Calpain inhibitor, BS 17

    Gene Symbol: CAST

    分子量

    126 kDa

    基因ID

    831

    UniProt

    P20810
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