Calpastatin 抗体 (CF®647)
Quick Overview for Calpastatin 抗体 (CF®647) (ABIN7650445)
抗原
See all Calpastatin (CAST) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Calpastatin(CAST/1550), CF647 conjugate
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产品特性
- Calpastatin is an inhibitor of calpain (calcium-activated intracellular cysteine protease). Calpastatin regulates calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpastatin co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human CAST protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: HeLa cells. Esophagus or Small Intestine.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- Calpastatin (CAST)
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别名
- Calpastatin
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背景
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Synonyms: Calpastatin, Calpain inhibitor, BS 17
Gene Symbol: CAST
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分子量
- 126 kDa
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基因ID
- 831
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UniProt
- P20810
抗原
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