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BTLA 抗体

This anti-BTLA antibody is a 小鼠 单克隆 antibody detecting BTLA in . Suitable for 人.
产品编号 ABIN7649798
发货至: 中国

Quick Overview for BTLA 抗体 (ABIN7649798)

抗原

See all BTLA 抗体
BTLA (B and T Lymphocyte Associated (BTLA))

适用

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小鼠

克隆类型

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单克隆

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This BTLA antibody is un-conjugated

应用范围

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克隆位点

BTLA-1528
  • 原理

    BTLA(BTLA/1528)

    产品特性

    B and T lymphocyte attenuator (BTLA) is a member of the CD28 Ig superfamily of inhibitory co-receptors, along with CTLA-4 and PD-1. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family receptors. Rather, it is engaged by herpesvirus entry mediator (HVEM), a member of the TNF receptor superfamily, leading to an inhibited immune response. It also plays a role in immune tolerance. BTLA is expressed on most CD4 and CD8 T cells, B cells, macrophages, dentritic cells, and NK cell. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human BTLA protein

    亚型

    IgG2b, kappa
  • 应用备注

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    说明

    Positive Control: Human lymph node or MDAMB468 xenograft.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, no BSA, no azide

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at -20 °C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    BTLA (B and T Lymphocyte Associated (BTLA))

    别名

    BTLA

    背景

    Synonyms: BTLA, B and T lymphocyte associated protein, B and T lymphocyte attenuator, CD272

    Gene Symbol: BTLA

    分子量

    33 kDa

    基因ID

    151888

    途径

    Cancer Immune Checkpoints
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