Reelin 抗体
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- 抗原 See all Reelin (RELN) 抗体
- Reelin (RELN)
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Reelin antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RELN
- 亚型
- IgG
- Top Product
- Discover our top product RELN Primary Antibody
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- 应用备注
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IHC-P 1:100-500
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C
- 有效期
- 12 months
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- 抗原
- Reelin (RELN)
- 别名
- Reln/Reelin (RELN 产品)
- 背景
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Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).
Subcellular location: Extracellular, Secreted
Synonyms: RL, ETL7, LIS2, PRO1598, Reelin, RELN
- 基因ID
- 5649
- UniProt
- P78509
- 途径
- Synaptic Membrane
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