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CXCR1 抗体 (AA 186-280)

This anti-CXCR1 antibody is a 兔 多克隆 antibody detecting CXCR1 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 大鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN730873
发货至: 中国

Quick Overview for CXCR1 抗体 (AA 186-280) (ABIN730873)

抗原

See all CXCR1 抗体
CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

适用

  • 49
  • 18
  • 12
  • 2
人, 大鼠

宿主

  • 49
  • 9
  • 3
  • 1
  • 1

克隆类型

  • 50
  • 10
  • 2
多克隆

标记

  • 33
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CXCR1 antibody is un-conjugated

应用范围

  • 45
  • 22
  • 21
  • 18
  • 16
  • 12
  • 12
  • 9
  • 7
  • 7
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 186-280

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CXCR1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Schneberger, Gordon, DeVasure, Boten, Heires, Romberger, Wyatt: "CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks lung inflammation in swine barn dust-instilled mice." in: Pulmonary pharmacology & therapeutics, Vol. 31, pp. 55-62, (2015) (PubMed).

    Zhao, Zhu, Jiang, Xu, Wang, Chen, Liu: "Role of GPER1, EGFR and CXCR1 in differentiating between malignant follicular thyroid carcinoma and benign follicular thyroid adenoma." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 11236-47, (2015) (PubMed).

    Tang, Yang, Wang, Li, Xu, Chen, Liu: "High expression of GPER1, EGFR and CXCR1 is associated with lymph node metastasis in papillary thyroid carcinoma." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3213-23, (2015) (PubMed).

    Tian, Lv, Yang, Zhang, Yu, Zhu, Xiao, Zhu: "Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3028-37, (2014) (PubMed).

  • 抗原

    CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

    别名

    CXCR1

    背景

    Synonyms: C-C, CD128, CD181, CKR-1, IL8R1, IL8RA, CMKAR1, IL8RBA, CDw128a, C-C-CKR-1, C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1, CXCR1

    Background: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

    基因ID

    3577

    UniProt

    P25024

    途径

    cAMP Metabolic Process
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