CXCR1 抗体 (Extracellular, N-Term)
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Quick Overview for CXCR1 抗体 (Extracellular, N-Term) (ABIN7043037)
抗原
See all CXCR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-16, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to CXCR1 Chemokine Receptor
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预测反应
- Specific to human CXCR1
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产品特性
- Anti-Human CXCR1 (extracellular) Antibody is directed against an extracellular epitope of the human CXCR1. Anti-Human CXCR1 (extracellular) Antibody (ABIN7043037 and ABIN7044163) can be used for western blot and indirect flow cytometry applications. It has been designed to recognize human CXCR1.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)SNITDPQMW DFDDLN, corresponding to amino acid residues 2-16 of human CXCR1
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (C-Term) antibody
KO Validated CXCR1 适用: 人 ICC, IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 186-280) antibodyCXCR1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 250-350) antibodyCXCR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B8A1 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) antibodyCXCR1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 26-38) antibodyVerified CXCR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 330-341) antibodyCXCR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (N-Term) antibodyCXCR1 适用: 人 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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别名
- CXCR1
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背景
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Synonyms: C-X-C chemokine receptor type 1, Interleukin-8 receptor A, IL-8R A, IL8RA, IL-8 receptor type 1, CD181
Description: Chemokine receptors belong to the seven transmembrane domain G-protein coupled receptor superfamily and are differentially expressed in diverse cell types. In leukocytes, chemokines coordinate development, differentiation, anatomic distribution, trafficking, and effector functions and thereby regulate innate and adaptive immune responses.To date, 18 chemokine receptors are known and designated as CXCR1-5, CCR1-11, XCR1, and CX3CR1 based on their specific chemokine preferences.The CXC chemokine receptors specifically bind and respond to cytokines of the CXC chemokine family. CXCR1 and CXCR2 were the first chemokine receptor subtypes to be defined. They are the only known mammalian receptors for ELR+ CXC chemokines [CXC chemokines which contain the tripeptide motif glutamic acid-leucine-arginine (ELR) N-terminal to the first cysteine].CXCR1 and CXCR2 both bind IL-8, with high affinity, they do not bind other types of chemokines. CXCR1 and CXCR2 are the major chemokine receptors expressed on neutrophils. They appear to operate mainly in acute inflammation and innate immunity.
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基因ID
- 3577
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NCBI登录号
- NM_000634
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UniProt
- P25024
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途径
- cAMP Metabolic Process
抗原
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