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C5 抗体 (AA 701-755) (Biotin)

This anti-C5 antibody is a 兔 多克隆 antibody detecting C5 in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN727877
发货至: 中国

Quick Overview for C5 抗体 (AA 701-755) (Biotin) (ABIN727877)

抗原

See all C5 抗体
C5 (Complement Component 5 (C5))

适用

  • 125
  • 34
  • 23
  • 16
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 117
  • 21
  • 4
  • 3

克隆类型

  • 125
  • 20
多克隆

标记

  • 61
  • 12
  • 11
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This C5 antibody is conjugated to Biotin

应用范围

  • 80
  • 50
  • 43
  • 39
  • 38
  • 17
  • 14
  • 13
  • 13
  • 10
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 22
    • 15
    • 14
    • 12
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-755

    交叉反应

    人, 小鼠

    预测反应

    Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse C5a (725-770aa)

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    C5 (Complement Component 5 (C5))

    别名

    C5a anaphylatoxin

    背景

    Synonyms: C5, He, C5a, Complement C5, Hemolytic complement, Hc

    Background: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.

    基因ID

    15139

    UniProt

    P06684

    途径

    Complement System, Carbohydrate Homeostasis
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