FGL2 抗体 (AA 75-150)
Quick Overview for FGL2 抗体 (AA 75-150) (ABIN727785)
抗原
See all FGL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-150
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from rat FGL2
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance." in: Science (New York, N.Y.), Vol. 348, Issue 6234, pp. 589-94, (2015) (PubMed).
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: "Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance." in: Science (New York, N.Y.), Vol. 348, Issue 6234, pp. 589-94, (2015) (PubMed).
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- FGL2 (Fibrinogen-Like 2 (FGL2))
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别名
- FGL2
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背景
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Synonyms: Fibroleukin, Cytotoxic T-lymphocyte-specic protein, Fibrinogen-like protein 2, Fibrinogen like protein 2, Prothrombinase, Fibroleukin, pT49, T49, G3V7P2_RAT, Fibrinogen-like 2.
Background: FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.
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基因ID
- 84586
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UniProt
- G3V7P2
抗原
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